Is clubbing a feature of the anti-phospholipid antibody syndrome?

نویسندگان

  • A W Harris
  • T A Harding
  • M D Gaitonde
  • J D Maxwell
چکیده

A patient with the anti-phospholipid antibody syndrome and digital clubbing is described. No recognized cause for the clubbing was found. It is suggested that platelet aggregation and microthrombi formation as a result of anti-phospholipid antibody may be involved in the pathogenesis of the digital clubbing. This may be a new feature of the anti-phospholipid antibody.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New clinical and laboratory finding in anti-phospholipid syndromes

Antiphospholipid syndrome (APS) is a systemic autoimmune disease with the appearance of anti-phospholipid antibody (ACLA), Anti β2GPI and lupus anticoagulant (LAC) in serum. The antigen-antibody reaction on cell surface leads to thrombosis, miscarriage and inflammation. Clinical findings are diverse and include thrombosis in veins and arteries, pregnancy loss, thrombocytopenia, neurological and...

متن کامل

THE PREVALENCE OF ANTIPHOSPHOLIPI D SYNDROME IN PATIENTS WI TH RECURRENT PREGNANCY LOSS: A REPORT FROM SOUTH OF IR AN

In order to determine the role of different anti-phospholipid antibodies as an etiologic factor in recurrent pregnancy failure, a prospective study was done on one-hundred and thirty-eight women who had unexplained recurrent pregnancy loss (group I) with one-hundred well-matched women with normal reproductive outcome allocated as control group (GIl). Sera from 138 patients and 100 controls...

متن کامل

گزارش موردی نادر از وقوع ترومبوز شریانی با تظاهر ایسکمی اندام تحتانی در دو بیمار مبتلا به گرانولوماتوز وگنر

Introduction: Wegener’s Granolomatosis (WG) is a systemic, necrotizing, small-vessel vasculitis. Vascular inflammation and occlusion leading to tissue ischemia is a hallmark of WG. WG has a clinical predilection for the upper airways, lungs, and kidneys. Thromboembolic events do not usually occur and arterial thrombosis is extremely rare. Case Report: Here we reported 2 rare cases of arteria...

متن کامل

Importance of Anti-GRP78 Antibody in Pre-Eclampsia

Background: Preeclampsia (PE) is a pregnancy specific syndrome that is associated with high maternal and fetal morbidity and mortality. Glucose regulated protein78 (GRP78) is an Endoplasmic Reticulum (ER) protein which is expressed on the cell surfaces of trophoblast cells under stress or hypoxic condition. GRP78 has a role in aggressive behavior of invasive cells and may play a role in normal ...

متن کامل

The Anti-β2GP1 Autoantibody Level in Serum of Pregnant Women with History of Recurrent Miscarriage

Abstract Background and objectives: Recurrent miscarriage (RM) is one of the most common reproductive disorders, generally considered to be the loss of three or more pregnancies before viability. One of the causes of this disorder is the immunological factors such as autoantibodies associated with anti-phospholipid syndrome. Material and Methods: this case-control study was conducted on ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Postgraduate medical journal

دوره 69 815  شماره 

صفحات  -

تاریخ انتشار 1993